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It is important to take this medication exactly as prescribed by your doctorIf you miss a dosetake it as soon as possible and continue with your regular scheduleIf it is almost time for your next doseskip the missed dose and continue with your regular dosing scheduleDo not take a double dose to make up for a missed oneIf you are not sure what to do after missing a dosecontact your doctor or pharmacist for advice.

Chlorpropamide’s plasma half-life may be prolonged by Zyloprimsince Zyloprim and chlorpropamide may compete for excretion in the renal tubuleThe risk of hypoglycemia secondary to this mechanism may be increased if Zyloprim and chlorpropamide are given concomitantly in the presence of renal insufficiency.

Zyloprim and its primary active metaboliteoxipurinolare eliminated by the kidneysthereforechanges in renal function have a profound effect on dosageIn patients with decreased renal function or who have concurrent illnesses which can affect renal function such as hypertension and diabetes mellitusperiodic laboratory parameters of renal functionparticularly BUN and serum creatinine or creatinine clearanceshould be performed and the patient’s dosage of Zyloprim reassessed.

This list is not complete and other drugs may interact with ZyloprimTell your doctor about all medications you useThis includes prescriptionover-the-countervitaminand herbal productsDo not start a new medication without telling your doctor.

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continue to take zyloprim and talk to your doctor if you experience an upset stomach or diarrhea headache, dizziness or drowsiness and an acute attack of gouty arthritis side effects other than those listed here may also occur.

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